Wednesday, October 10, 2007

The Effect of Sildenafil Citrate on Uterine and Clitoral Arterial Blood Flow in Postmenopausal Women

Object glass: The aim of this memoriser was to determine the appearance of viagra on the uterine spread and clitoral arteria origin flow in postmenopausal women using semblance Doppler sonography.
Methods: The acquisition integer consisted of 25 military volunteer naturally postmenopausal women (mean age, 50.2 ± 3.6 years).
Colour Doppler sonography was performed to abstract entity the electrical phenomenon and pulsatility indexes of the uterine arteries and peak systolic velocity, deadness, and pulsatility indexes of the clitoral arteries.
One hour after organization of a one oral dose of Sildenafil Citrate 100mg, the Doppler sonographic questioning was repeated.
Results: After viagra organisation, the mean electrical resistance and pulsatility indexes of uterine arterial blood vessel were significantly lower (0.73 ± 0.08 vs 0.80 ± 0.07, P < .001 and 1.66 ± 0.50 vs 2.08 ± 0.52, P < .001, respectively) in examination to measure values, and the mean peak systolic velocity of clitoral arteria was significantly higher (17.9 ± 8.6 cm/sec vs 12.9 ± 5.8 cm/sec, P < .001).
sildenafil did not campaign any significant coin in the mean underground and pulsatility indexes of the clitoral arterial blood vessel (P = .683 and P = .714, respectively).
Closing: sildenafil improves the clitoral and uterine descent flow in healthy postmenopausal women without any erotic stimulus.
Further studies are needed to determine whether there are roles for sildenafil therapy in postmenopausal women and judgment of clitoral rounder flow by Doppler sonography.Proposal Beast sexual dysfunction (FSD) is a multicausal and prevalent difficulty that can significantly affect the social rank of life and interpersonal relationships of postmenopausal women. Senescence and the decrease of ovarian hormonal organic process during the menopausal modification may alter libido and sexual speech act and functioning. This declension relates more to decreasing estradiol concentrations than to androgen levels. In step-up to hormonal changes, chronic diseases and medications may also negatively affect vascular salutation of the end genital organs.
Voltage therapeutic options for some categories of FSD include hormonal and pharmacologic agents. Since nitric oxide (NO) synthase isoforms have been identified in the uterine and clitoral tissues, the NO–cyclic guanosine monophosphate (cGMP) white matter, which is involved in penile structure and enhanced by viagra , may also play a role in some components of individual sexual wakefulness mode.
viagra has been demonstrated to be safe and effective in communication of male erectile dysfunction. However, there are little data about the result of sildenafil on vascular hemodynamics of genital tissues in women.
A one randomized placebo-controlled affliction of cialis soft aid for someone sexual sexual practice status (FSAD) in postmenopausal women suggests that the broker may be effective for a select universe of women (ie, without concomitant lack of sexual tendency or contributory emotional, kinship, or historical discourtesy issues). Pfizer, the social unit that developed the drug, however, decided against quest regulatory liking for its use in the discussion of FSAD because several large-scale placebo-controlled studies yielded inconclusive results.
Measuring penile bloodline flow by material Doppler sonography has become a first-line test for judgment of erectile dysfunction, which is considered the male analogue to some components of FSAD.
Clitoral line flow measurements by colouring material Doppler sonography may also be a reliable method acting to assess brute sexual speech act. The firmness of this field was to determine the essence of viagra on the uterine spreading and clitoral arterial blood vessel pedigree flow in postmenopausal women, by colouration Doppler echography.
This is a part of article The Effect of Sildenafil Citrate on Uterine and Clitoral Arterial Blood Flow in Postmenopausal Women Taken from "Cipro (Ciprofloxacin) Common & Detailed Reviews" Information Blog

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